Journal of Yeungnam Medical Science

Sung Sae Han

12 Articles

Hybrid Coronary Revascularization: Sung Sae Han; Yeungnam Univ J Med. 2007;24(2 Suppl):S36-48. Published online December 31, 2007; DOI: https://doi.org/10.12701/yujm.2007.24.2S.S36

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Abstract PDF: Hybrid coronary revascularization combines left internal mammary artery (LIMA) to left anterior descending artery (LAD) grafting integrated with percutaneous coronary intervention (PCI) on stenoses in the non-LAD territories. Hybrid coronary revascularization offers multivessel revascularization with minimal morbidity in high risk patients. Usually hybrid coronary revascularization performs minimally invasive direct coronary artery bypass grafting (MIDCAB) without cardiopulmonary bypass. The concept is now 10 year old. This procedure has been developed from MIDCAB plus percutaneous transluminal coronary angioplasty (PTCA) to totally endoscopic coronary artery bypass grafting (TECAB) procedures plus PTCA and drug-eluting stenting (DES). The hybrid coronary revascularization procedure may be especially useful in complex LAD lesions, restenotic lesions in LAD, acute myocardial infarction in “non-LAD” territory, high-risk elderly patients with multiple comorbidities and patients with severe left ventricular systolic dysfunction who are not ideal candidates for conventional bypass surgery. Hybrid coronary revascularization results according to the literature are very attractive. LIMA patency rates were found to be in the 98% range and restenosis rates in the PCI part of the procedure are in a 12% range.¹⁶⁾ The wider introduction of hybrid revascularization is limited chiefly by the high number of repeat interventions compared with off-pump coronary artery bypass grafting, which occurs because of the target vessel failure rate of percutaneous coronary intervention. Drug-eluting stents substantially decrease the reintervention rate. However, the future role of hybrid coronary revascularization is unclear in patients with multivessel coronary artery disease involving the LAD if comparable results may be attained with multivessel PCI.

Myocardial Protective Effect of Histidine-Tryptophan-Ketoglutarate Solution and Cold Blood Cardioplegic Solution in Pediatric Cardiac Surgery.: Tae Eun Jung, Dong Hyup Lee, Sung Sae Han; Yeungnam Univ J Med. 2006;23(1):19-25. Published online June 30, 2006; DOI: https://doi.org/10.12701/yujm.2006.23.1.19

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Abstract PDF: BACKGROUND
There is limited data on comparisons between the effect of histidine-tryptophan-ketoglutarate (HTK) solution and cold blood cardioplegic (CBC) solution in pediatric cardiac surgery. The purpose of this study was to compare the myocardial protective effect of HTK solution and CBC solution in patients undergoing pediatric cardiac surgery. MATERILAS AND METHODS: We selected 49 patients with ventricular septal defect and atrial septal defect. HTK solution was used in 21 patients and CBC solution was used in 28 patents. HTK solution was given as a single dose, whereas CBC solution was used in the usual multi-dose method. The incidence of EKG change and concentration of Troponin T and CK-MB were compared for the evaluation of myocardial damage. RESULTS: There were no significant differences in the incidence of ST, T segment change by EKG and serial cardiac enzyme levels between two groups. CONCLUSION: These results suggested that the myocardial protective effect of HTK solution was similar to CBC solution in simple pediatric cardiac surgery.

Clinical Analysis of Patch Repair of Ventricular Septal Defect in Infant.: Tae Eun Jung, Jang Hoon Lee, Dong Hyup Lee, Jung Cheul Lee, Sung Sae Han, Sae Yeun Kim, Dae Lim Ji; Yeungnam Univ J Med. 2002;19(2):99-106. Published online December 31, 2002; DOI: https://doi.org/10.12701/yujm.2002.19.2.99

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Abstract PDF: BACKGROUND
Simple ventricular septal defect(VSD) is the most common congenital heart disease. Although closure of VSD is currently associated with a relatively low risk, experience with younger and smaller infants has been variably less satisfactory. We assessed the results of surgical closure of VSD in infant. MATERIALS AND METHODS: Between 1996 and 2000, 45 non-restrictive VSD patients underwent patch repair and retrospective analysis was done. Patients were divided into two groups based on weight: group I infants weighed 5kg or less(n=16), and group II infants weighed more than 5kg(n=29). Both groups had similar variation in sex, VSD location, aortic cross clamp time and total bypass time. But combined diseases (ASD, PDA, MR) were more in group I. We closed VSD with patch and used simple continuous suture method in all patients. RESULTS: There were no operative mortality, no reoperation for hemodynamically significant residual shunt and no surgically induced complete heart block. As a complication, pneumonia(group I: 2 cases, group II: 2 cases), transient seizure(group II: 2), wound infection(group I: 1, group II: 1), urinary tract infection(group I: 1) and chylopericardium(group I: 1) developed, and there was no significant difference between two groups(p>0.05). CONCLUSION: Early primary closure with simple continuous suture method was applicable in all patients with non-restrictive VSD without any serious complications.

Two cases report of bronchial carcinoid tumors.: Kyo Won Choi, Jeong Ill Suh, Sung Suk Kim, Jin Hong Chung, Kwan Ho Lee, Hyun Woo Lee, Dong Hyup Lee, Jung Cheul Lee, Sung Sae Han; Yeungnam Univ J Med. 1993;10(2):525-536. Published online December 31, 1993; DOI: https://doi.org/10.12701/yujm.1993.10.2.525

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Abstract PDF: Bronchial carcinoid tumor was a low grade malignant and it was regarded as predictable clinical course and good survivality after surgical resection. But despite of its low grade malignant potentiality, bronchial carcinoid tumor was clearly capable of metastasizing and causing death. We present 2 cases of bronchial carcinoid tumors. One of them was typical carcinoid tumor in 44 year-old female and another was atypical carcinoid tumor in 53 year-old male patient. Currative therapeutic procedure was performed by lobectomy and wedge resection.

An aortic dissection in pregnant woman - a case report -.: Hyeong Min Lee, Eun Pyo Hong, Dong Hyup Lee, Jung Cheul Lee, Sung Sae Han, Dong Gu Sin, Young Jo Kim, Bong Sup Shim; Yeungnam Univ J Med. 1993;10(1):253-259. Published online June 30, 1993; DOI: https://doi.org/10.12701/yujm.1993.10.1.253

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Abstract PDF

We have experienced a case of aortic dissecting aneurysm in pregnant woman. She felt initially severe chest pain which was radiated to the neck on the 3days before delivery. Thereafter dyspnea and generalized edema were developed for 1 month after delivery. She was diagnosed as aortic dissectLn, Debakey type-II. During cardiopulmonary bypass, the selective cerebral perfusion was done through the right and left commom carotid arteries. Aortic replacement with Hemashield vascular graft and reimplantation of innominate artery, resuspension of aortic valve, repair of intimal tear were performed. The postoperative course was uneventful.

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A Case of Ascending Aortic Dissection with Severe Aortic Regurgitation Diagnosed by Echocardiography
Sung-Hee Kim, Ok-Kyoung Lee
The Korean Journal of Clinical Laboratory Science.2020; 52(4): 425. CrossRef

Clinical observation of aortic dissection.: Byeong Ik Jang, Jin Ho Park, Dong Ku Shin, Yeoung Jo Kim, Bong Sup Shim, Hyun Woo Lee, Su Hyen Kim, Sung Sae Han; Yeungnam Univ J Med. 1992;9(2):334-341. Published online December 31, 1992; DOI: https://doi.org/10.12701/yujm.1992.9.2.334

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Abstract PDF: A clinical review of 34 cases of aortic dissection which were admitted to Yeungnam University hospital between March 1983 and April 1992. The results are as follows: 1. The peak incidence was in 5th, 6th decade and male to female ratio was 1.83:1. 2. The most common cause of aortic dissection was atherosclerosis and hypertension (79%). 3. The most common presenting symptom was pain (73%). but dyspnea, palpable mass, murmur, shock were also observed. 4. Abnormal electrocardiographic finding was myocardial ischemia in 6 cases, arrhythmia in 5 cases, LVH in 5 cases. 5. The X-ray findings showed abnormal aortic contour in 10 cases but normal X-ray finding was observed in 63% of DeBaKey Type III. 6. The most common diagnostic procedure was echocardiogram and abdominal Ultrasonography. 7. The mortality of all cases was 20%, operation mortality was 18% but no death of medically treatment in medical indication.

Surgical treatment of atrial septal defect in adult patients.: Dong Hyup Lee, Jung Cheul Lee, Sung Sae Han; Yeungnam Univ J Med. 1992;9(2):321-326. Published online December 31, 1992; DOI: https://doi.org/10.12701/yujm.1992.9.2.321

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Abstract PDF: The study consisted of all patients over 35yerars old undergoing surgical repair of atrial septal defect for the period from June 1985, to August 1992. The following results were observed. 1. ASD was closed with patch in 11 (73%) patients. 2. The relationship of pulmonary artery systolic pressure to Qp/Qs ratio was not significant. 3. Before operation 6 patients were in NYHA functional class II. 8 were in class III, After operation 8 patients were in class I, 6 were in class II. 4. Atrial fibrillation has persisted in 3 patients and returned regular rhythm in 1 patient after surgery. 5. There was no operative mortality and we had good surgical results regardless of patient's age.

Clinical Observations of the Solitary Pulmonary Nodules.: Jin Woo Roh, Byeong Ik Jang, Jong Sun Park, Jin Hong Chung, Hyung Woo Lee, Kwan Ho Lee, Hyun Woo Lee, Jung Cheul Lee, Sung Sae Han; Yeungnam Univ J Med. 1990;7(2):141-149. Published online December 31, 1990; DOI: https://doi.org/10.12701/yujm.1990.7.2.141

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Abstract PDF: The authors conducted a clinical observation of 55 cases of solitary pulmonary nodules at Yeungnam University Hospital from June 1986 to October 1990, and the following results were obtained: 1. The age distribution was ranged from 18 to 77 years, and the male-to female ratio was 1.8:1. 2. Among 55 cases of nodules, 28 cases were benign and 27 cases were malignant nodules, and of malignant nodules, the primary lung cancer was 23 cases and of benign nodules, 18 cases were tuberculoma. 3. 23 cases (41.8%) was asymptomatic and the other 32 cases were symptomatic; chest pain 12 cases, hemoptysis; 8 cases, cough; 8 cases and dyspnea; 4 cases. 4. The non-smoker-to-smoker ratio was 1:1.04, but among 23 smoker over 20 pack years, 14 cases were malignant nodules. 5. According to nodular size, there is no striking differences between benign and malignant nodules except 3-4 cm sized nodules. 6. The lobar distribution of nodules, 35 cases were in the right lung (upper lobe; 14 cases, middle lobe; 11 cases, and lower lobe; 10 cases) and 23 cases were in the left lung (upper lobe; 9 cases, lower lobe; 11 cases), and the malignant nodules were most commonly observed in the right upper lung.

Pulmonary atresia with intact ventricular septum.: Sung Sae Han; Yeungnam Univ J Med. 1990;7(1):11-18. Published online June 30, 1990; DOI: https://doi.org/10.12701/yujm.1990.7.1.11

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Abstract PDF: No abstract available.

A Case of Dissection in Marfan Syndrome with Ascending Aortic Aneurysm.: Bong Young Yoon, Chang Heon Yang, Young Jo Kim, Bong Sup Shim, Hyun Woo Lee, Han Young Ryu, Tae Eun Jung, Yee Tae Park, Sung Sae Han; Yeungnam Univ J Med. 1989;6(1):179-184. Published online June 30, 1989; DOI: https://doi.org/10.12701/yujm.1989.6.1.179

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Abstract PDF: The Marfan syndrome is a generalized connective tissue disease involving eye, musculoskeletal system, cardiovascular system, and inherited autosomal dominant with various expression type. The cardiovascular complications such as aortic aneurysm, aortic dissection, aortic regurgitation, mitral regurgitation and aortic dissection which usually occurs in previously normal sized aorta are poor prognostic factors. However, the aortic dissection which developed in patient with Marfan syndrome and aortic aneurysm was rare. We experienced one case of dissecting aneurysm in patient diagnosed as previous aortic aneurysm, aortic regurgitation, and Marfan syndrome, receiving successful operation.

Effects of Dimethyl Sulfoxide on the Differentiation of Myocardial and Endothelial Cells.: Dong Hyup Lee, Yee Tae Park, Sung Sae Han, Yung Chang Lee; Yeungnam Univ J Med. 1988;5(2):111-119. Published online December 31, 1988; DOI: https://doi.org/10.12701/yujm.1988.5.2.111

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Abstract PDF: To elucidate the effects of dimethyl sulfoxide on of myocardial and endothelial cells in culture, the cells were exposed to 10% dimethyl sulfoxide in culture medium for 1 hour at 48 hours after cell isolation. The general morphology and the cytochemical reaction of marker enzymes for mitochondria and Golgi complexes were investigated. The results were summarized as follows 1. DMSO induced elongation and narrowing of the cells and increase of mitochondrial reaction in myocardial cells. 2. DMSO induced destruction and disruption of myofibrils in myocardial cells resulting in increase of contractile activities. 3. In the endothelial cells, DMSO suppressed proliferative activities but thiamine pyrophosphatase reactions were enhanced indicating increase of Golgi complex activity. 4. DMSO seemed to hamper with the adhesiveness and motility of the endothelial cells causing the decrease of the number of cells in vitro.

Clinical Study of 459 Cases Cardiovascular Surgery.: Han Young Ryu, Tae Eun Jung, Yee Tae Park, Sung Sae Han; Yeungnam Univ J Med. 1988;5(2):101-110. Published online December 31, 1988; DOI: https://doi.org/10.12701/yujm.1988.5.2.101

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Abstract PDF: Between April, 1984 and September 1988, 459 patients underwent cardiovascular surgery at the Yeungnam University Hospital. Of these, 355 cases were open heart surgeries and 104 cases were non-open heart surgeries. There were 237 patients of acyanotic congenital cardiac anomalies, 40 patients of cyanotic congenital cardiac anomalies, and 85 patients of acquired heart diseases. The sex ratio of cardiovascular diseases was represented as 1:1.3 in male and female. The age distribution was ranged from 1 day to 65 years old. The common congenital cardiovascular anomalies were ventricular septal defect (38.7%), patent ductus arteriosus (25.5%), atrial septal defect (20.7%), Tetralogy of Fallot (8.3%), and pulmonary stenosis (2.4%) in order of frequency. Among 87 acquired cardiovascular diseases, 81 patients underwent operation for cardiac valvular lesions, 51 patients had mitral valve replacement and 13 patients had aortic valve replacement and 17 patients had double valve replacement. The overall mortality of cardiovascular surgery was 3.3% and mortality of open heart surgery was 3.9%.

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